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| Cat.No | ACP18532 | Target Name | LAMTOR4 |
|---|---|---|---|
| Target Synonyms | AV006840; C7orf59; CG059_HUMAN; Chromosome 7 open reading frame 59 ; Late endosomal/lysosomal adaptor and MAPK and MTOR activator 4; Ragulator complex protein LAMTOR4; UPF0539 protein C7orf59 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-99 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q0VGL1 |
|---|
Uniprot Id
Q0VGL1
Target Species
Human
Target Name
LAMTOR4
Target Full Name
Ragulator complex protein LAMTOR4
Target Function
As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated.
Target Subcellular Location
Lysosome.
Target Protein Families
LAMTOR4 family
Target Synonyms
AV006840; C7orf59; CG059_HUMAN; Chromosome 7 open reading frame 59 ; Late endosomal/lysosomal adaptor and MAPK and MTOR activator 4; Ragulator complex protein LAMTOR4; UPF0539 protein C7orf59
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