Recombinant Human Ventral anterior homeobox 2 (VAX2)

ACP18968

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Specifications

Cat.No	ACP18968	Target Name	VAX2
Target Synonyms	VAX2; Ventral anterior homeobox 2	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Expression Range	1-290
Protein Length	Full length protein	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q9UIW0

Background Information

Uniprot Id

Q9UIW0
Target Species

Human
Target Name

VAX2
Target Full Name

Ventral anterior homeobox 2
Target Function

Transcription factor that may function in dorsoventral specification of the forebrain. Regulates the expression of Wnt signaling antagonists including the expression of a truncated TCF7L2 isoform that cannot bind CTNNB1 and acts therefore as a potent dominant-negative Wnt antagonist. Plays a crucial role in eye development and, in particular, in the specification of the ventral optic vesicle. May be a regulator of axial polarization in the retina.
Target Subcellular Location

Nucleus.
Target Protein Families

EMX homeobox family
Target Synonyms

VAX2; Ventral anterior homeobox 2

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Recombinant Human Ventral anterior homeobox 2 (VAX2)

Specifications

Immunogen Information

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