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| Cat.No | ACP19528 | Target Name | PODN |
|---|---|---|---|
| Target Synonyms | 9430070G18; LRRGT00160; MGC24995; PCAN; Podn; PODN_HUMAN; Podocan; Podocan proteoglycan; RP23 40G2.7; SLRR5A | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 20-613 |
| Protein Length | Full Length of Mature Protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q7Z5L7 |
|---|
Uniprot Id
Q7Z5L7
Target Species
Human
Target Name
PODN
Target Full Name
Podocan
Target Function
Negatively regulates cell proliferation and cell migration.
Target Subcellular Location
[Isoform 1]: Secreted, extracellular space, extracellular matrix.; [Isoform 2]: Cytoplasm.; [Isoform 3]: Cytoplasm.; [Isoform 4]: Cytoplasm.
Target Protein Families
Small leucine-rich proteoglycan (SLRP) family, SLRP class V subfamily
Target Tissue Specificity
Kidney, heart, liver, pancreas and vascular smooth muscle cells. Also detected in aortic intima (at protein level).
Target Synonyms
9430070G18; LRRGT00160; MGC24995; PCAN; Podn; PODN_HUMAN; Podocan; Podocan proteoglycan; RP23 40G2.7; SLRR5A
Target Background
The protein encoded by this gene is a member of the small leucine-rich repeat protein family and contains an amino terminal CX3CXCX7C cysteine-rich cluster followed by a leucine-rich repeat domain. Studies suggest that this protein could function to inhibit smooth muscle cell proliferation and migration following arterial injury.
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