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| Cat.No | ACP20084 | Target Name | ERVK-21 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Protein Length | Partial | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P61565 |
|---|
Uniprot Id
P61565
Target Species
Human
Target Name
ERVK-21
Target Full Name
Endogenous retrovirus group K member 21 Env polyprotein
Target Function
Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. This endogenous envelope protein has lost its original fusogenic properties.; SU mediates receptor recognition.; TM anchors the envelope heterodimer to the viral membrane through one transmembrane domain. The other hydrophobic domain, called fusion peptide, mediates fusion of the viral membrane with the target cell membrane.
Target Subcellular Location
[Transmembrane protein]: Cell membrane; Single-pass type I membrane protein.; [Surface protein]: Cell membrane; Peripheral membrane protein.; [Endogenous retrovirus group K member 21 Env polyprotein]: Virion.
Target Protein Families
Beta type-B retroviral envelope protein family, HERV class-II K(HML-2) env subfamily
Target Synonyms
ERVK-21Endogenous retrovirus group K member 21 Env polyprotein; EnvK1 protein; Envelope polyprotein; HERV-K_12q14.1 provirus ancestral Env polyprotein) [Cleaved into: Surface protein; SU); Transmembrane protein; TM)]
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