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Recombinant Human HIV Tat-specific factor 1 (HTATSF1)

ACP20928

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Specifications

Cat.No	ACP20928	Target Name	HTATSF1
Target Synonyms	HTATSF1HIV Tat-specific factor 1; Tat-SF1	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Expression Range	2-755
Protein Length	Full Length of Mature Protein	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	O43719

Background Information

Uniprot Id

O43719
Target Species

Human
Target Name

HTATSF1
Target Full Name

17S U2 SnRNP complex component HTATSF1
Target Function

Functions as a general transcription factor playing a role in the process of transcriptional elongation. May mediate the reciprocal stimulatory effect of splicing on transcriptional elongation. In case of infection by HIV-1, it is up-regulated by the HIV-1 proteins NEF and gp120, acts as a cofactor required for the Tat-enhanced transcription of the virus.
Target Subcellular Location

Nucleus.
Target Protein Families

HTATSF1 family
Target Tissue Specificity

Widely expressed.
Target Synonyms

HTATSF1HIV Tat-specific factor 1; Tat-SF1
Target Background

The protein encoded by this gene functions as a cofactor for the stimulation of transcriptional elongation by HIV-1 Tat, which binds to the HIV-1 promoter through Tat-TAR interaction. This protein may also serve as a dual-function factor to couple transcription and splicing and to facilitate their reciprocal activation. Alternatively spliced transcript variants have been found for this gene.

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Recombinant Human HIV Tat-specific factor 1 (HTATSF1)

Specifications

Immunogen Information

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