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Recombinant Human GDNF family receptor alpha-3 (GFRA3)

ACP21104

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Specifications

Cat.No	ACP21104	Target Name	GFRA3
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Expression Range	32-374	Protein Length	Full Length of Mature Protein
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	O60609

Background Information

Uniprot Id

O60609
Target Species

Human
Target Name

GFRA3
Target Full Name

GDNF family receptor alpha-3
Target Function

Receptor for the glial cell line-derived neurotrophic factor, ARTN (artemin). Mediates the artemin-induced autophosphorylation and activation of the RET receptor tyrosine kinase.
Target Subcellular Location

Cell membrane; Lipid-anchor, GPI-anchor.
Target Protein Families

GDNFR family
Target Tissue Specificity

Widely expressed in adult and fetus which exhibit a similar pattern. Essentially not expressed in the central nervous system, but highly expressed in several sensory and sympathetic ganglia of the peripheral nervous system. Moderate expression in many non
Target Synonyms

GDNF family receptor alpha 3; GDNF family receptor alpha-3; GDNF receptor alpha-3; GDNFR-alpha-3; GDNFR3; GFR-alpha-3; GFRA3; GFRA3_HUMAN; Glial cell line derived neurotrophic factor receptor alpha 3 ; GPI linked receptor; OTTHUMP00000159486; OTTHUMP00000224020
Target Background

The protein encoded by this gene is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor and a member of the GDNF receptor family. It forms a signaling receptor complex with RET tyrosine kinase receptor and binds the ligand, artemin.

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Recombinant Human GDNF family receptor alpha-3 (GFRA3)

Specifications

Immunogen Information

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