Recombinant Human Fatty acid-binding protein, brain (FABP7)

Uniprot Id

O15540

Target Species

Human

Target Name

FABP7

Target Full Name

Fatty acid-binding protein, brain

Target Function

B-FABP could be involved in the transport of a so far unknown hydrophobic ligand with potential morphogenic activity during CNS development. It is required for the establishment of the radial glial fiber system in developing brain, a system that is necessary for the migration of immature neurons to establish cortical layers.

Target Subcellular Location

Cytoplasm.

Target Protein Families

Calycin superfamily, Fatty-acid binding protein (FABP) family

Target Tissue Specificity

Expressed in brain and other neural tissues.

Target Synonyms

B FABP; B-FABP; BFABP; BLBP; Brain lipid binding protein; Brain lipid-binding protein; Brain-type fatty acid-binding protein; DKFZp547J2313; FABP 7; FABP7; FABP7_HUMAN; FABPB; Fatty Acid Binding Protein 7; Fatty acid binding protein 7 brain; Fatty acid binding protein brain; Fatty acid-binding protein 7; Fatty acid-binding protein, brain; Mammary derived growth inhibitor related ; Mammary-derived growth inhibitor related; MRG; OTTHUMP00000017119

Target Background

The gene encodes a small, highly conserved cytoplasmic protein that bind long-chain fatty acids and other hydrophobic ligands. The encoded protein is important in the establishment of the radial glial fiber in the developing brain. Alternative splicing and promoter usage results in multiple transcript variants encoding different isoforms. Pseudogenes of this gene are found on multiple chromosomes.