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| Cat.No | ACP21728 | Target Name | HS3ST1 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 21-307 | Protein Length | Full Length of Mature Protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O14792 |
|---|
Uniprot Id
O14792
Target Species
Human
Target Name
HS3ST1
Target Full Name
Heparan sulfate glucosamine 3-O-sulfotransferase 1
Target Function
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to position 3 of glucosamine residues in heparan. Catalyzes the rate limiting step in the biosynthesis of heparan sulfate (HSact). This modification is a crucial step in the biosynthesis of anticoagulant heparan sulfate as it completes the structure of the antithrombin pentasaccharide binding site.
Target Subcellular Location
Golgi apparatus lumen.
Target Protein Families
Sulfotransferase 1 family
Target Tissue Specificity
Highly expressed in the brain and kidney and weakly expressed in the heart, lung and placenta.
Target Synonyms
3-OST-1; 3OST; 3OST1; EC 2.8.2.23 ; h3 OST 1; h3-OST-1; Heparan sulfate (glucosamine) 3 O sulfotransferase 1; Heparan sulfate 3 O sulfotransferase 1; Heparan sulfate 3-O-sulfotransferase 1; Heparan sulfate D glucosaminyl 3 O sulfotransferase 1; Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1; Heparan sulfate glucosamine 3-O-sulfotransferase 1; Heparin glucosamine 3 O sulfotransferase; HS3S1_HUMAN; HS3ST 1; Hs3st1
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