Recombinant Human Homeobox protein Hox-A7 (HOXA7)

Uniprot Id

P31268

Target Species

Human

Target Name

HOXA7

Target Full Name

Homeobox protein Hox-A7

Target Function

Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

Target Subcellular Location

Nucleus.

Target Protein Families

Antp homeobox family

Target Synonyms

ANTP; Antp, Drosophila, homolog of; Homeobox 1A; Homeobox A7; Homeobox protein Hox 1.1; Homeobox protein Hox A7; Homeobox protein Hox-1A; Homeobox protein Hox-A7; HOX1; HOX1.1; HOX1.1, mouse, homolog of; Hox1A; HOXA7; HXA7_HUMAN; OTTHUMP00000024835

Target Background

In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. For example, the encoded protein represses the transcription of differentiation-specific genes during keratinocyte proliferation, but this repression is then overcome by differentiation signals. This gene is highly similar to the antennapedia (Antp) gene of Drosophila.