Recombinant Human Tyrosine-protein phosphatase non-receptor type 4 (PTPN4), Truncated

Cat.No	ACP23361	Target Name	PTPN4
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Protein Length	Partial	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Cat.No

ACP23361

Target Name

PTPN4

Form

Lyophilized powder

Expression System

Custom Production. Please inquire and provide the desire expression system.

Protein Length

Partial

Purity

>85% (SDS-PAGE)

Storage Buffer

5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Target Species	Human	Uniprot ID	P29074

Background Information

Uniprot Id

P29074
Target Species

Human
Target Name

PTPN4
Target Full Name

Tyrosine-protein phosphatase non-receptor type 4
Target Function

Phosphatase that plays a role in immunity, learning, synaptic plasticity or cell homeostasis. Regulates neuronal cell homeostasis by protecting neurons against apoptosis. Negatively regulates TLR4-induced interferon beta production by dephosphorylating adapter TICAM2 and inhibiting subsequent TRAM-TRIF interaction. Dephosphorylates also the immunoreceptor tyrosine-based activation motifs/ITAMs of the TCR zeta subunit and thereby negatively regulates TCR-mediated signaling pathway. May act at junctions between the membrane and the cytoskeleton.
Target Subcellular Location

Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cytoplasm.
Target Protein Families

Protein-tyrosine phosphatase family, Non-receptor class subfamily
Target Synonyms

MEG; megakaryocyte phosphatase; megakaryocyte protein-tyrosine phosphatase; Protein tyrosine phosphatase MEG1; Protein tyrosine phosphatase; megakaryocyte; protein tyrosine phosphatase; non-receptor type 4 (megakaryocyte); Protein-tyrosine phosphatase MEG1; PTN4; PTN4_HUMAN; PTPase MEG1; PTPase-MEG1; PTPMEG; PTPMEG1; Ptpn4; Tyrosine protein phosphatase non receptor type 4; Tyrosine-protein phosphatase non-receptor type 4
Target Background

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. This PTP has been shown to interact with glutamate receptor delta 2 and epsilon subunits, and is thought to play a role in signalling downstream of the glutamate receptors through tyrosine dephosphorylation.

Recombinant Human Tyrosine-protein phosphatase non-receptor type 4 (PTPN4), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human Tyrosine-protein phosphatase non-receptor type 4 (PTPN4), Truncated Now

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