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Rabbit anti-Human CTNNA3 Polyclonal Antibody

The antibody against CTNNA3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human CTNNA3 (NP_001278062.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.

ADA-00225A

The antibody against CTNNA3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human CTNNA3 (NP_001278062.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.

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Specifications


Cat.No ADA-00225A ClonalityPolyclonal
Host SpeciesRabbitTarget NameCTNNA3
Target SynonymsVR22; ARVD13; CTNNA3FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesRat brain, 293T, LO2, Mouse spleenApplicationELISA, WB, IF/ICC, IHC-P

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human CTNNA3 (NP_001278062.1).Target SpeciesHuman
Uniprot IDQ9UI47Immunogen Sequence
Background Information
  • Uniprot Id

    Q9UI47

  • Target Species

    Human

  • Target Name

    CTNNA3

  • Target Full Name

    Catenin alpha-3

  • Target Function

    May be involved in formation of stretch-resistant cell-cell adhesion complexes.

  • Target Involvement

    Arrhythmogenic right ventricular dysplasia, familial, 13 (ARVD13)

  • Target Subcellular Location

    Cytoplasm, cytoskeleton.

  • Target Protein Families

    Vinculin/alpha-catenin family

  • Target Tissue Specificity

    Predominantly expressed in heart and testis. Expressed at lower levels in brain, kidney, liver and skeletal muscle.

  • Target Synonyms

    4930429L08Rik; 4933408A16; Alpha catenin like protein; Alpha T catenin; Alpha T-catenin; Cadherin associated protein ; Cadherin-associated protein; Catenin alpha 3; Catenin alpha-3; Catna3; CTNA3_HUMAN; CTNNA3; MGC26194; MGC75041; OTTHUMP00000019684; OTTMUSP00000028119; OTTMUSP00000028120; RP11-433J16.1; VR22

  • Target Background

    This gene encodes a protein that belongs to the vinculin/alpha-catenin family. The encoded protein plays a role in cell-cell adhesion in muscle cells. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia, familial 13. Alternative splicing results in multiple transcript variants.

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