Rabbit anti-Human RFK Polyclonal Antibody

The antibody against RFK was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-155 of human RFK (NP_060809.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-01042A

Number

Cat.No	ADA-01042A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	RFK
Target Synonyms	RIFK; RFK	Form	Liquid
Species Reactivity	Human, Mouse	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	HeLa, 293T, Mouse brain, Mouse small intestine, U-87MG	Application	ELISA, WB

Cat.No

ADA-01042A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

RFK

Target Synonyms

RIFK; RFK

Form

Liquid

Species Reactivity

Human, Mouse

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

HeLa, 293T, Mouse brain, Mouse small intestine, U-87MG

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 1-155 of human RFK (NP_060809.3).	Target Species	Human
Immunogen Sequence	MRHLPYFCRGQVVRGFGRGSKQLGIPTANFPEQVVDNLPADISTGIYYGWASVGSGDVHKMVVSIGWNPYYKNTKKSMETHIMHTFKEDFYGEILNVAIVGYLRPEKNFDSLESLISAIQGDIEEAKKRLELPEHLKIKEDNFFQVSKSKIMNGH	Uniprot ID	Q969G6

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 1-155 of human RFK (NP_060809.3).

Target Species

Human

Immunogen Sequence

MRHLPYFCRGQVVRGFGRGSKQLGIPTANFPEQVVDNLPADISTGIYYGWASVGSGDVHKMVVSIGWNPYYKNTKKSMETHIMHTFKEDFYGEILNVAIVGYLRPEKNFDSLESLISAIQGDIEEAKKRLELPEHLKIKEDNFFQVSKSKIMNGH

Uniprot ID

Q969G6

Background Information

Uniprot Id

Q969G6
Target Species

Human
Target Name

RFK
Target Full Name

Riboflavin kinase
Target Function

Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin-mononucleotide (FMN), hence rate-limiting enzyme in the synthesis of FAD. Essential for TNF-induced reactive oxygen species (ROS) production. Through its interaction with both TNFRSF1A and CYBA, physically and functionally couples TNFRSF1A to NADPH oxidase. TNF-activation of RFK may enhance the incorporation of FAD in NADPH oxidase, a critical step for the assembly and activation of NADPH oxidase.
Target Subcellular Location

Cytoplasm.
Target Tissue Specificity

Detected in brain, placenta and urinary bladder.
Target Synonyms

0610038L10Rik; AF031381; ATP:riboflavin 5' phosphotransferase; ATP:riboflavin 5''-phosphotransferase; Flavokinase; FLJ11149; KOI 4; Rfk; Riboflavin kinase; RIFK; RIFK_HUMAN; RP11-422N19.2
Target Background

Riboflavin kinase (RFK; EC 2.7.1.26) is an essential enzyme that catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN), an obligatory step in vitamin B2 utilization and flavin cofactor synthesis (Karthikeyan et al., 2003 [PubMed 12623014]).

Rabbit anti-Human RFK Polyclonal Antibody

Specifications

Immunogen Information

Inquire Rabbit anti-Human RFK Polyclonal Antibody Now

Related Products