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The antibody against GRIN3B was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 180-410 of human GRIN3B (NP_619635.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against GRIN3B was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 180-410 of human GRIN3B (NP_619635.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-01249A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | GRIN3B |
| Target Synonyms | NR3B; GluN3B; GRIN3B | Form | Liquid |
| Species Reactivity | Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Rat brain | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 180-410 of human GRIN3B (NP_619635.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | O60391 | Immunogen Sequence |
Uniprot Id
O60391
Target Species
Human
Target Name
GRIN3B
Target Full Name
Glutamate receptor ionotropic, NMDA 3B
Target Function
NMDA receptor subtype of glutamate-gated ion channels with reduced single-channel conductance, low calcium permeability and low voltage-dependent sensitivity to magnesium. Mediated by glycine.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane.
Target Protein Families
Glutamate-gated ion channel (TC 1.A.10.1) family, NR3B/GRIN3B subfamily
Target Synonyms
GluN3B; Glutamate [NMDA] receptor subunit 3B; Glutamate receptor ionotropic N methyl D aspartate 3B ; Glutamate receptor ionotropic NMDA 3B; GRIN3B; N-methyl-D-aspartate receptor subtype 3B; NMD3B_HUMAN; NMDA receptor subunit 3B; NMDA type glutamate receptor subunit NR3B; NMDAR3B; NR3B
Target Background
The protein encoded by this gene is a subunit of an N-methyl-D-aspartate (NMDA) receptor. The encoded protein is found primarily in motor neurons, where it forms a heterotetramer with GRIN1 to create an excitatory glycine receptor. Variations in this gene have been proposed to be linked to schizophrenia.
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