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The antibody against GZMK was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 27-264 of human GZMK (NP_002095.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against GZMK was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 27-264 of human GZMK (NP_002095.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-01340A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | GZMK |
| Target Synonyms | TRYP2; GZMK | Form | Liquid |
| Species Reactivity | Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse liver, Rat liver | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 27-264 of human GZMK (NP_002095.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P49863 | Immunogen Sequence |
Uniprot Id
P49863
Target Species
Human
Target Name
GZMK
Target Full Name
Granzyme K
Target Subcellular Location
Secreted. Cytoplasmic granule.
Target Protein Families
Peptidase S1 family, Granzyme subfamily
Target Tissue Specificity
Expressed in lung, spleen, thymus and peripheral blood leukocytes.
Target Research Area
Cell Biology
Target Synonyms
Fragmentin 3; Fragmentin-3; Fragmentin3; GRAK_HUMAN; Granzyme 3; granzyme K (granzyme 3; tryptase II); granzyme K (serine protease; granzyme 3; tryptase II); Granzyme K; Granzyme K precursor; Granzyme-3; Granzyme3; GranzymeK; GZMK; NK TRYP 2; NK TRYP2; NK tryptase 2; NK-TRYP-2; NK-tryptase-2; NKTRYP2; Serine protease granzyme 3; TRYP 2; TRYP2; Tryptase II; TryptaseII
Target Background
This gene product is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here lacks consensus sequences for N-glycosylation present in other granzymes.
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