Rabbit anti-Human CD30 Polyclonal Antibody

The antibody against CD30 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 500-595 of human CD30 (NP_001234.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-02390A

Number

Cat.No	ADA-02390A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	CD30
Target Synonyms	CD30; Ki-1; D1S166E	Form	Liquid
Species Reactivity	Human	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	HeLa, H460, Jurkat	Application	ELISA, WB

Cat.No

ADA-02390A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

CD30

Target Synonyms

CD30; Ki-1; D1S166E

Form

Liquid

Species Reactivity

Human

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

HeLa, H460, Jurkat

Application

ELISA, WB

Immunogen Description	A synthetic peptide corresponding to a sequence within amino acids 500-595 of human CD30 (NP_001234.3).	Target Species	Human
Immunogen Sequence	LPEPRVSTEHTNNKIEKIYIMKADTVIVGTVKAELPEGRGLAGPAEPELEEELEADHTPHYPEQETEPPLGSCSDVMLSVEEEGKEDPLPTAASGK	Uniprot ID	P28908

Immunogen Description

A synthetic peptide corresponding to a sequence within amino acids 500-595 of human CD30 (NP_001234.3).

Target Species

Human

Immunogen Sequence

LPEPRVSTEHTNNKIEKIYIMKADTVIVGTVKAELPEGRGLAGPAEPELEEELEADHTPHYPEQETEPPLGSCSDVMLSVEEEGKEDPLPTAASGK

Uniprot ID

P28908

Background Information

Uniprot Id

P28908
Target Species

Human
Target Name

TNFRSF8
Target Full Name

Tumor necrosis factor receptor superfamily member 8
Target Function

Receptor for TNFSF8/CD30L. May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa-B.
Target Subcellular Location

[Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Cytoplasm.
Target Tissue Specificity

[Isoform 2]: Detected in alveolar macrophages (at protein level).
Target Synonyms

TNFRSF8; CD30; D1S166E; Tumor necrosis factor receptor superfamily member 8; CD30L receptor; Ki-1 antigen; Lymphocyte activation antigen CD30; CD antigen CD30
Target Background

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Rabbit anti-Human CD30 Polyclonal Antibody

Specifications

Immunogen Information

Inquire Rabbit anti-Human CD30 Polyclonal Antibody Now

Related Products