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The antibody against SRSF4 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human SRSF4 (NP_005617.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against SRSF4 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human SRSF4 (NP_005617.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-02761A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SRSF4 |
| Target Synonyms | SFRS4; SRP75; SRSF4 | Form | Liquid |
| Species Reactivity | Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse liver, Rat thymus, Rat uterus | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human SRSF4 (NP_005617.2). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | MPRVYIGRLSYQARERDVERFFKGYGKILEVDLKNGYGFVEFDDLRDADDAVYELNGKDLCGERVIVEHARGPRRDGSYGSGRSGYGYRRSGRDKYGPPTRTEYRLIVENLSSRCSWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSR | Uniprot ID | Q08170 |
Uniprot Id
Q08170
Target Species
Human
Target Name
SRSF4
Target Full Name
Serine/arginine-rich splicing factor 4
Target Function
Plays a role in alternative splice site selection during pre-mRNA splicing. Represses the splicing of MAPT/Tau exon 10.
Target Subcellular Location
Nucleus speckle.
Target Protein Families
Splicing factor SR family
Target Synonyms
SFRS4; SRP75; SRSF4
Target Background
Enables RNA binding activity. Involved in negative regulation of mRNA splicing, via spliceosome. Located in nuclear speck. Biomarker of Down syndrome; acute myeloid leukemia; clear cell renal cell carcinoma; and colon adenocarcinoma.
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