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Rabbit anti-Human CMPK1 Polyclonal Antibody

The antibody against CMPK1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 69-228 of human CMPK1 (NP_057392.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, IP, ELISA.

ADA-02963A

The antibody against CMPK1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 69-228 of human CMPK1 (NP_057392.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, IP, ELISA.

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Specifications


Cat.No ADA-02963A ClonalityPolyclonal
Host SpeciesRabbitTarget NameCMPK1
Target SynonymsCK; CMK; UMK; CMPK; UMPK; UMP-CMPK; CMPK1FormLiquid
Species ReactivityHuman, MouseIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesHeLa, Mouse kidney, 293T, HL-60, HT-29, Mouse brainApplicationELISA, WB, IF/ICC, IP

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 69-228 of human CMPK1 (NP_057392.1).Target SpeciesHuman
Immunogen SequenceLLRDERKNPDSQYGELIEKYIKEGKIVPVEITISLLKREMDQTMAANAQKNKFLIDGFPRNQDNLQGWNKTMDGKADVSFVLFFDCNNEICIERCLERGKSSGRSDDNRESLEKRIQTYLQSTKPIIDLYEEMGKVKKIDASKSVDEVFDEVVQIFDKEGUniprot IDP30085
Background Information
  • Uniprot Id

    P30085

  • Target Species

    Human

  • Target Name

    CMPK1

  • Target Full Name

    UMP-CMP kinase

  • Target Function

    Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity.

  • Target Subcellular Location

    Nucleus. Cytoplasm.

  • Target Protein Families

    Adenylate kinase family, UMP-CMP kinase subfamily

  • Target Tissue Specificity

    Ubiquitously expressed.

  • Target Synonyms

    CMK; CMPK 1; CMPK; cmpk1; Cytidine monophosphate (UMP CMP) kinase 1 cytosolic; Cytidine monophosphate kinase; Cytidine monophosphate UMP CMP kinase 1 cytosolic; Cytidylate kinase; dCMP kinase; Deoxycytidylate kinase; EC 2.7.4.14; KCY; KCY_HUMAN; Monophosphatase kinase; OTTHUMP00000009565; RP11 511I2.1; UCK; UMK; UMP CMP; UMP CMP kinase; UMP-CMP kinase; UMP/CMP kinase; UMP/CMPK; UMPK; Uridine monophosphate kinase; Uridine monophosphate/cytidine monophosphate kinase

  • Target Background

    This gene encodes one of the enzymes required for cellular nucleic acid biosynthesis. This enzyme catalyzes the transfer of a phosphate group from ATP to CMP, UMP, or dCMP, to form the corresponding diphosphate nucleotide. Alternate splicing results in both coding and non-coding transcript variants.

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