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The antibody against DGCR14 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human DGCR14 (NP_073210.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against DGCR14 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human DGCR14 (NP_073210.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-03484A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | DGCR14 |
| Target Synonyms | ES2; DGSH; DGSI; bis1; DGS-H; DGS-I; ESS-2; Es2el; DGCR13; DGCR14 | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | NIH/3T3, A-549, Mouse testis, Mouse thymus | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human DGCR14 (NP_073210.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q96DF8 | Immunogen Sequence |
Uniprot Id
Q96DF8
Target Species
Human
Target Name
ESS2
Target Full Name
Splicing factor ESS-2 homolog
Target Function
May be involved in pre-mRNA splicing.
Target Subcellular Location
Nucleus.
Target Protein Families
ESS2 family
Target Tissue Specificity
Highly expressed in heart, brain and skeletal muscle. Detected at low levels in placenta.
Target Synonyms
DGC14_HUMAN; DGCR13; DGCR14; DGS H; DGS I; DGS-H; DGSH; DGSI; DiGeorge syndrome critical region 13; DiGeorge syndrome critical region 14; DiGeorge syndrome critical region gene 14; DiGeorge syndrome critical region gene DGSI; DiGeorge syndrome critical region protein 14; DiGeorge syndrome gene H; DiGeorge syndrome gene I; DiGeorge syndrome protein H; ES2; ES2 protein ; Es2el; Protein DGCR14; Protein ES2
Target Background
This gene is located within the minimal DGS critical region (MDGCR) thought to contain the gene(s) responsible for a group of developmental disorders. These disorders include DiGeorge syndrome, velocardiofacial syndrome, conotruncal anomaly face syndrome, and some familial or sporadic conotruncal cardiac defects which have been associated with microdeletion of 22q11.2. The encoded protein may be a component of C complex spliceosomes, and the orthologous protein in the mouse localizes to the nucleus. Alternatively spliced transcript variants have been found for this gene.
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