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Rabbit anti-Human GLRA2 Polyclonal Antibody

The antibody against GLRA2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 350-420 of human GLRA2 (NP_002054.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-04914A

The antibody against GLRA2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 350-420 of human GLRA2 (NP_002054.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-04914A ClonalityPolyclonal
Host SpeciesRabbitTarget NameGLRA2
Target SynonymsGLR; MRXSP; GLRA2FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesA-431, Mouse spinal cord, U-87MGApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 350-420 of human GLRA2 (NP_002054.1).Target SpeciesHuman
Immunogen SequenceRLRRRQKRQNKEEDVTRESRFNFSGYGMGHCLQVKDGTAVKATPANPLPQPPKDGDAIKKKFVDRAKRIDTUniprot IDP23416
Background Information
  • Uniprot Id

    P23416

  • Target Species

    Human

  • Target Name

    GLRA2

  • Target Full Name

    Glycine receptor subunit alpha-2

  • Target Function

    Glycine receptors are ligand-gated chloride channels. Channel opening is triggered by extracellular glycine. Channel opening is also triggered by taurine and beta-alanine. Plays a role in the down-regulation of neuronal excitability. Contributes to the generation of inhibitory postsynaptic currents. Plays a role in cellular responses to ethanol.

  • Target Subcellular Location

    Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell junction, synapse. Cell membrane; Multi-pass membrane protein. Cell projection.

  • Target Protein Families

    Ligand-gated ion channel (TC 1.A.9) family, Glycine receptor (TC 1.A.9.3) subfamily, GLRA2 sub-subfamily

  • Target Synonyms

    GLR; Glra2; GLRA2_HUMAN; Glycine receptor alpha 2 polypeptide; Glycine receptor alpha 2 subunit; Glycine receptor subunit alpha 2; Glycine receptor subunit alpha-2; Gycine receptor alpha 2

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