Rabbit anti-Human PXK Polyclonal Antibody

The antibody against PXK was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human PXK (NP_060241.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-05044A

Number

Cat.No	ADA-05044A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	PXK
Target Synonyms	SLOB; MONAKA; PXK	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	HepG2, Jurkat, Mouse lung, Mouse spleen, Rat kidney, U-251MG	Application	ELISA, WB

Cat.No

ADA-05044A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

PXK

Target Synonyms

SLOB; MONAKA; PXK

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

HepG2, Jurkat, Mouse lung, Mouse spleen, Rat kidney, U-251MG

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human PXK (NP_060241.2).	Target Species	Human
Immunogen Sequence	MAFMEKPPAGKVLLDDTVPLTAAIEASQSLQSHTEYIIRVQRGISVENSWQIVRRYSDFDLLNNSLQIAGLSLPLPPKKLIGNMDREFIAERQKGLQNYLNVITTNHILSNCELVKKFLDPNNYSANYTEIALQQVSMFFRSEPKWEVVEPLKDIGWRIRKKYFLMKIKNQPKERLVLSWADLGPDKYLSDKDFQCLIKL	Uniprot ID	Q7Z7A4

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human PXK (NP_060241.2).

Target Species

Human

Immunogen Sequence

MAFMEKPPAGKVLLDDTVPLTAAIEASQSLQSHTEYIIRVQRGISVENSWQIVRRYSDFDLLNNSLQIAGLSLPLPPKKLIGNMDREFIAERQKGLQNYLNVITTNHILSNCELVKKFLDPNNYSANYTEIALQQVSMFFRSEPKWEVVEPLKDIGWRIRKKYFLMKIKNQPKERLVLSWADLGPDKYLSDKDFQCLIKL

Uniprot ID

Q7Z7A4

Background Information

Uniprot Id

Q7Z7A4
Target Species

Human
Target Name

PXK
Target Full Name

PX domain-containing protein kinase-like protein
Target Function

Binds to and modulates brain Na,K-ATPase subunits ATP1B1 and ATP1B3 and may thereby participate in the regulation of electrical excitability and synaptic transmission. May not display kinase activity.
Target Subcellular Location

Cytoplasm. Cell membrane; Peripheral membrane protein. Note=Also associates with the plasma membrane. Isoform 3 is present throughout the cell.
Target Protein Families

Protein kinase superfamily
Target Tissue Specificity

Widely expressed in all tissues examined except in heart. Isoform 1 is expressed in high levels in the brain, skeletal muscle, spleen and testis. Isoform 7 expression has yet to be demonstrated.
Target Synonyms

FLJ20335; K-ATPase; Modulator of Na; Modulator of Na K ATPase ; Modulator of Na K ATPase long form ; MONaKA; PX domain containing protein kinase like protein ; PX domain containing serine/threonine kinase ; PX domain-containing protein kinase-like protein; PX ser/thr kinase v2 ; PX serine/threonine kinase ; Pxk; PXK_HUMAN
Target Background

This gene encodes a phox (PX) domain-containing protein which may be involved in synaptic transmission and the ligand-induced internalization and degradation of epidermal growth factors. Variations in this gene may be associated with susceptibility to systemic lupus erythematosus (SLE). Alternative splicing results in multiple transcript variants.

Rabbit anti-Human PXK Polyclonal Antibody

Specifications

Immunogen Information

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