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The antibody against IQGAP2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1330-1440 of human IQGAP2 (NP_006624.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
The antibody against IQGAP2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1330-1440 of human IQGAP2 (NP_006624.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
| Cat.No | ADA-05092A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | IQGAP2 |
| Target Synonyms | IQGAP2 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Jurkat, Mouse liver | Application | ELISA, WB, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1330-1440 of human IQGAP2 (NP_006624.2). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | QQEVDHATDMVSRAMIDSRTPEEMKHSQSMIEDAQLPLEQKKRKIQRNLRTLEQTGHVSSENKYQDILNEIAKDIRNQRIYRKLRKAELAKLQQTLNALNKKAAFYEEQIN | Uniprot ID | Q13576 |
Uniprot Id
Q13576
Target Species
Human
Target Name
IQGAP2
Target Full Name
Ras GTPase-activating-like protein IQGAP2
Target Function
Binds to activated CDC42 and RAC1 but does not seem to stimulate their GTPase activity. Associates with calmodulin.
Target Tissue Specificity
Isoform 2 expression is enhanced in testis.
Target Synonyms
IQ motif containing GTPase activating protein 2; IQGA2_HUMAN; Iqgap2; Ras GTPase activating-like protein; Ras GTPase-activating-like protein IQGAP2
Target Background
This gene encodes a member of the IQGAP family. The encoded protein contains three IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. This protein interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. It also acts as a tumor suppressor and has been found to play a role in regulating innate antiviral responses. Alternative splicing results in multiple transcript variants.
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