Rabbit anti-Human DLX5 Polyclonal Antibody

The antibody against DLX5 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 200 to the C-terminus of human DLX5 (NP_005212.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-05299A

Number

Cat.No	ADA-05299A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	DLX5
Target Synonyms	SHFM1; SHFM1D; DLX5	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	HeLa, 293T, U-251MG	Application	ELISA, WB

Cat.No

ADA-05299A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

DLX5

Target Synonyms

SHFM1; SHFM1D; DLX5

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

HeLa, 293T, U-251MG

Application

ELISA, WB

Immunogen Description	A synthetic peptide corresponding to a sequence within amino acids 200 to the C-terminus of human DLX5 (NP_005212.1).	Target Species	Human
Immunogen Sequence	EMPPEHSPSSSDPMACNSPQSPAVWEPQGSSRSLSHHPHAHPPTSNQSPASSYLENSASWYTSAASSINSHLPPPGSLQHPLALASGTLY	Uniprot ID	P56178

Immunogen Description

A synthetic peptide corresponding to a sequence within amino acids 200 to the C-terminus of human DLX5 (NP_005212.1).

Target Species

Human

Immunogen Sequence

EMPPEHSPSSSDPMACNSPQSPAVWEPQGSSRSLSHHPHAHPPTSNQSPASSYLENSASWYTSAASSINSHLPPPGSLQHPLALASGTLY

Uniprot ID

P56178

Background Information

Uniprot Id

P56178
Target Species

Human
Target Name

DLX5
Target Full Name

Homeobox protein DLX-5
Target Function

Transcriptional factor involved in bone development. Acts as an immediate early BMP-responsive transcriptional activator essential for osteoblast differentiation. Stimulates ALPL promoter activity in a RUNX2-independent manner during osteoblast differentiation. Stimulates SP7 promoter activity during osteoblast differentiation. Promotes cell proliferation by up-regulating MYC promoter activity. Involved as a positive regulator of both chondrogenesis and chondrocyte hypertrophy in the endochondral skeleton. Binds to the homeodomain-response element of the ALPL and SP7 promoter. Binds to the MYC promoter. Requires the 5'-TAATTA-3' consensus sequence for DNA-binding.
Target Involvement

Split-hand/foot malformation 1 with sensorineural hearing loss, autosomal recessive (SHFM1D)
Target Subcellular Location

Nucleus.
Target Protein Families

Distal-less homeobox family
Target Synonyms

DLX5Homeobox protein DLX-5
Target Background

This gene encodes a member of a homeobox transcription factor gene family similiar to the Drosophila distal-less gene. The encoded protein may play a role in bone development and fracture healing. Mutation in this gene, which is located in a tail-to-tail configuration with another member of the family on the long arm of chromosome 7, may be associated with split-hand/split-foot malformation.

Rabbit anti-Human DLX5 Polyclonal Antibody

Specifications

Immunogen Information

Inquire Rabbit anti-Human DLX5 Polyclonal Antibody Now

Related Products