Rabbit anti-Human TELO2 Polyclonal Antibody

The antibody against TELO2 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 450-550 of human TELO2 (NP_057195.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-05315A

Number

Cat.No	ADA-05315A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	TELO2
Target Synonyms	CLK2; TEL2; YHFS; TELO2	Form	Liquid
Species Reactivity	Human, Mouse	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	HeLa, K-562	Application	ELISA, WB

Cat.No

ADA-05315A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

TELO2

Target Synonyms

CLK2; TEL2; YHFS; TELO2

Form

Liquid

Species Reactivity

Human, Mouse

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

HeLa, K-562

Application

ELISA, WB

Immunogen Description	A synthetic peptide corresponding to a sequence within amino acids 450-550 of human TELO2 (NP_057195.2).	Target Species	Human
Immunogen Sequence	ASEAGTSLVPATAEPPAETPAEIVDGGVPQAQLAGSDSDLDSDDEFVPYDMSGDRELKSSKAPAYVRDCVEALTTSEDIERWEAALRALEGLVYRSPTATR	Uniprot ID	Q9Y4R8

Immunogen Description

A synthetic peptide corresponding to a sequence within amino acids 450-550 of human TELO2 (NP_057195.2).

Target Species

Human

Immunogen Sequence

ASEAGTSLVPATAEPPAETPAEIVDGGVPQAQLAGSDSDLDSDDEFVPYDMSGDRELKSSKAPAYVRDCVEALTTSEDIERWEAALRALEGLVYRSPTATR

Uniprot ID

Q9Y4R8

Background Information

Uniprot Id

Q9Y4R8
Target Species

Human
Target Name

TELO2
Target Full Name

Telomere length regulation protein TEL2 homolog
Target Function

Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals. May be involved in telomere length regulation.
Target Involvement

You-Hoover-Fong syndrome (YHFS)
Target Subcellular Location

Cytoplasm. Membrane. Nucleus. Chromosome, telomere.
Target Protein Families

TEL2 family
Target Synonyms

CLK2; hCLK2; KIAA0683; Protein clk-2 homolog; TEL2; TEL2 telomere maintenance 2 homolog; TEL2, telomere maintenance 2, homolog; telo2; TELO2_HUMAN; Telomere length regulation protein TEL2 homolog; Telomere maintenance 2
Target Background

This gene encodes a protein that functions as an S-phase checkpoint protein in the cell cycle. The protein may also play a role in DNA repair.

Rabbit anti-Human TELO2 Polyclonal Antibody

Specifications

Immunogen Information

Inquire Rabbit anti-Human TELO2 Polyclonal Antibody Now

Related Products