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The antibody against EHD4 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 362-541 of human EHD4 (NP_644670.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against EHD4 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 362-541 of human EHD4 (NP_644670.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-06054A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | EHD4 |
| Target Synonyms | PAST4; EHD4 | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, Mouse heart, 293T, Mouse brain | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 362-541 of human EHD4 (NP_644670.1). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | MQEQLENYDFTKFHSLKPKLIEAVDNMLSNKISPLMNLISQEETSTPTQLVQGGAFDGTTEGPFNQGYGEGAKEGADEEEWVVAKDKPVYDELFYTLSPINGKISGVNAKKEMVTSKLPNSVLGKIWKLADCDCDGMLDEEEFALAKHLIKIKLDGYELPSSLPPHLVPPSHRKSLPKAD | Uniprot ID | Q9H223 |
Uniprot Id
Q9H223
Target Species
Human
Target Name
EHD4
Target Full Name
EH domain-containing protein 4
Target Function
ATP- and membrane-binding protein that probably controls membrane reorganization/tubulation upon ATP hydrolysis. Plays a role in early endosomal transport.
Target Subcellular Location
Early endosome membrane; Peripheral membrane protein; Cytoplasmic side. Recycling endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Target Protein Families
TRAFAC class dynamin-like GTPase superfamily, Dynamin/Fzo/YdjA family, EHD subfamily
Target Tissue Specificity
Highly expressed in pancreas and heart.
Target Synonyms
EHD4; HCA10; HCA11; PAST4; FKSG7EH domain-containing protein 4; Hepatocellular carcinoma-associated protein 10/11; PAST homolog 4
Target Background
Enables cadherin binding activity. Involved in endocytic recycling and protein homooligomerization. Located in endoplasmic reticulum and recycling endosome membrane.
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