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Rabbit anti-Human LEPRE1 Polyclonal Antibody

The antibody against LEPRE1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 497-736 of human LEPRE1 (NP_071751.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-06447A

The antibody against LEPRE1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 497-736 of human LEPRE1 (NP_071751.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-06447A ClonalityPolyclonal
Host SpeciesRabbitTarget NameLEPRE1
Target SynonymsOI8; GROS1; LEPRE1FormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesHeLa, A375, HT-29, NCI-H460, SKOV3ApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 497-736 of human LEPRE1 (NP_071751.3).Target SpeciesHuman
Uniprot IDQ32P28Immunogen Sequence
Background Information
  • Uniprot Id

    Q32P28

  • Target Species

    Human

  • Target Name

    P3H1

  • Target Full Name

    Prolyl 3-hydroxylase 1

  • Target Function

    Basement membrane-associated chondroitin sulfate proteoglycan (CSPG). Has prolyl 3-hydroxylase activity catalyzing the post-translational formation of 3-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens, especially types IV and V. May be involved in the secretory pathway of cells. Has growth suppressive activity in fibroblasts.

  • Target Involvement

    Osteogenesis imperfecta 8 (OI8)

  • Target Subcellular Location

    [Isoform 1]: Endoplasmic reticulum.; Secreted, extracellular space, extracellular matrix.

  • Target Protein Families

    Leprecan family

  • Target Synonyms

    GROS 1; GROS1; Growth suppressor 1; LEPRE 1; Lepre1; Leprecan 1; Leprecan; Leprecan-1; Leprecan1; Leucine proline enriched proteoglycan (leprecan) 1; Leucine proline enriched proteoglycan 1; Leucine- and proline-enriched proteoglycan 1; MGC117314; OI8; P3H1; P3H1_HUMAN; Prolyl 3 hydroxylase 1; Prolyl 3-hydroxylase 1

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