Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
The antibody against KLF12 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 220-310 of human KLF12 (NP_009180.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
The antibody against KLF12 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 220-310 of human KLF12 (NP_009180.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
| Cat.No | ADA-07458A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | KLF12 |
| Target Synonyms | AP2REP; AP-2rep; HSPC122; KLF12 | Form | Liquid |
| Species Reactivity | Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Rat brain, Mouse brain | Application | ELISA, WB, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 220-310 of human KLF12 (NP_009180.3). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | GHGKAQMDPRGLSPRQSKSDSDDDDLPNVTLDSVNETGSTALSIARAVQEVHPSPVSRVRGNRMNNQKFPCSISPFSIESTRRQRRSESPD | Uniprot ID | Q9Y4X4 |
Uniprot Id
Q9Y4X4
Target Species
Human
Target Name
KLF12
Target Full Name
Krueppel-like factor 12
Target Function
Confers strong transcriptional repression to the AP-2-alpha gene. Binds to a regulatory element (A32) in the AP-2-alpha gene promoter.
Target Subcellular Location
Nucleus.
Target Protein Families
Sp1 C2H2-type zinc-finger protein family
Target Synonyms
2700063E05Rik; AI225908; AI315654; AP-2 repressor; AP-2rep; AP-2rep transcription factor; AP2REP; B130052C06Rik; D530033K05Rik; HSPC122; KLF12; KLF12 zinc finger transcriptional repressor; KLF12_HUMAN; Krueppel like factor 12; Krueppel-like factor 12; OTTHUMP00000018503; Transcriptional repressor AP 2rep ; Transcriptional repressor AP-2rep
Target Background
Activator protein-2 alpha (AP-2 alpha) is a developmentally-regulated transcription factor and important regulator of gene expression during vertebrate development and carcinogenesis. The protein encoded by this gene is a member of the Kruppel-like zinc finger protein family and can repress expression of the AP-2 alpha gene by binding to a specific site in the AP-2 alpha gene promoter. Repression by the encoded protein requires binding with a corepressor, CtBP1. Two transcript variants encoding different isoforms have been found for this gene.
Free shipping on orders $999+
Advenit post multos Scudilo Scutariorum tribunus velament
We accept credit cards, PayPal, and bank wires
Responsive and knowledgable customer service via email, text or phone
Notification
