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The antibody against AGPAT4 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 270-378 of human AGPAT4(NP_064518.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against AGPAT4 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 270-378 of human AGPAT4(NP_064518.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-08320A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | AGPAT4 |
| Target Synonyms | LPAAT4; LPLAT4; 1-AGPAT4; dJ473J16.2; LPAAT-delta; AGPAT4 | Form | Liquid |
| Species Reactivity | Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.05% proclin300, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse brain | Application | ELISA, WB |
| Immunogen Description | A synthetic peptide corresponding to a sequence within amino acids 270-378 of human AGPAT4(NP_064518.1). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | CSAWLHKLYQEKDAFQEEYYRTGTFPETPMVPPRRPWTLVNWLFWASLVLYPFFQFLVSMIRSGSSLTLASFILVFFVASVGVRWMIGVTEIDKGSAYGNSDSKQKLND | Uniprot ID | Q9NRZ5 |
Uniprot Id
Q9NRZ5
Target Species
Human
Target Name
AGPAT4
Target Full Name
1-acyl-sn-glycerol-3-phosphate acyltransferase delta
Target Function
Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone. Exhibits high acyl-CoA specificity for polyunsaturated fatty acyl-CoA, especially docosahexaenoyl-CoA (22:6-CoA, DHA-CoA).
Target Subcellular Location
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Target Protein Families
1-acyl-sn-glycerol-3-phosphate acyltransferase family
Target Tissue Specificity
Widely expressed with highest levels in skeletal muscle, followed by heart, liver, prostate and thymus.
Target Synonyms
AGPAT4; UNQ499/PRO1016; 1-acyl-sn-glycerol-3-phosphate acyltransferase delta; 1-acylglycerol-3-phosphate O-acyltransferase 4; 1-AGP acyltransferase 4; 1-AGPAT 4; Lysophosphatidic acid acyltransferase delta; LPAAT-delta
Target Background
This gene encodes a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. This integral membrane protein converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis.
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