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The antibody against ARR3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human ARR3 (NP_004303.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against ARR3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human ARR3 (NP_004303.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-09570A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ARR3 |
| Target Synonyms | ARRX; cArr; MYP26; ARR3 | Form | Liquid |
| Species Reactivity | Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse eye, Rat eye | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human ARR3 (NP_004303.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P36575 | Immunogen Sequence |
Uniprot Id
P36575
Target Species
Human
Target Name
ARR3
Target Full Name
Arrestin-C
Target Function
May play a role in an as yet undefined retina-specific signal transduction. Could bind to photoactivated-phosphorylated red/green opsins.
Target Subcellular Location
Photoreceptor inner segment. Cell projection, cilium, photoreceptor outer segment.
Target Protein Families
Arrestin family
Target Tissue Specificity
Inner and outer segments, and the inner plexiform regions of the retina.
Target Synonyms
ARR3; ARR4; ARRC_HUMAN; Arrestin 3 retinal; Arrestin 3 retinal (X-arrestin); Arrestin 4; Arrestin-C; ARRX; C arrestin; C-arrestin; CAR; cArr; Cone arrestin; Retinal cone arrestin 3; Retinal cone arrestin-3; X arrestin; X-arrestin
Target Background
The protein encoded by this gene is a non-visual arrestin which binds to agonist-activated, phosphorylated G protein-coupled receptors. This binding uncouples the receptor from the heterotrimeric G protein, resulting in termination of the G protein-coupled receptor signaling. The encoded protein also is a part of the centrosome, interacting with gamma-tubulin to help regulate proper centrosome function.
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