Rabbit anti-Human CPOX Polyclonal Antibody

The antibody against CPOX was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 111-454 of human CPOX (NP_000088.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-09786A

Number

Cat.No	ADA-09786A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	CPOX
Target Synonyms	COX; CPO; CPX; HCP; HARPO; CPOX	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	HeLa, A-549, A375, HepG2, Mouse liver, Rat liver	Application	ELISA, WB

Cat.No

ADA-09786A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

CPOX

Target Synonyms

COX; CPO; CPX; HCP; HARPO; CPOX

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

HeLa, A-549, A375, HepG2, Mouse liver, Rat liver

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 111-454 of human CPOX (NP_000088.3).	Target Species	Human
Uniprot ID	P36551	Immunogen Sequence

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 111-454 of human CPOX (NP_000088.3).

Target Species

Human

Uniprot ID

P36551

Immunogen Sequence

Background Information

Uniprot Id

P36551
Target Species

Human
Target Name

CPOX
Target Full Name

Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial
Target Function

Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
Target Involvement

Hereditary coproporphyria (HCP)
Target Subcellular Location

Mitochondrion intermembrane space.
Target Protein Families

Aerobic coproporphyrinogen-III oxidase family
Target Synonyms

Coprogen oxidase; COPROPORPHYRIA; Coproporphyrinogen III oxidase; Coproporphyrinogen Oxidase (CPOX); Coproporphyrinogen-III oxidase; Coproporphyrinogenase; COX; CPO; Cpox; CPX; HEM 6; Hem-6; Hem6; HEM6_HUMAN; mitochondrial
Target Background

The protein encoded by this gene is the sixth enzyme of the heme biosynthetic pathway. The encoded enzyme is soluble and found in the intermembrane space of mitochondria. This enzyme catalyzes the stepwise oxidative decarboxylation of coproporphyrinogen III to protoporphyrinogen IX, a precursor of heme. Defects in this gene are a cause of hereditary coproporphyria (HCP).

Rabbit anti-Human CPOX Polyclonal Antibody

Specifications

Immunogen Information

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