Rabbit anti-Human LEMD2 Polyclonal Antibody

The antibody against LEMD2 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 200-300 of human LEMD2 (NP_851853.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-10572A

Number

Cat.No	ADA-10572A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	LEMD2
Target Synonyms	LEM2; NET25; MARUPS; CTRCT42; dJ482C21.1; LEMD2	Form	Liquid
Species Reactivity	Mouse	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	Mouse brain	Application	ELISA, WB

Cat.No

ADA-10572A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

LEMD2

Target Synonyms

LEM2; NET25; MARUPS; CTRCT42; dJ482C21.1; LEMD2

Form

Liquid

Species Reactivity

Mouse

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

Mouse brain

Application

ELISA, WB

Immunogen Description	A synthetic peptide corresponding to a sequence within amino acids 200-300 of human LEMD2 (NP_851853.1).	Target Species	Human
Immunogen Sequence	PEVGRRLERWLSRLLLWASLGLLLVFLGILWVKMGKPSAPQEAEDNMKLLPVDCERKTDEFCQAKQKAALLELLHELYNFLAIQAGNFECGNPENLKSKCI	Uniprot ID	Q8NC56

Immunogen Description

A synthetic peptide corresponding to a sequence within amino acids 200-300 of human LEMD2 (NP_851853.1).

Target Species

Human

Immunogen Sequence

PEVGRRLERWLSRLLLWASLGLLLVFLGILWVKMGKPSAPQEAEDNMKLLPVDCERKTDEFCQAKQKAALLELLHELYNFLAIQAGNFECGNPENLKSKCI

Uniprot ID

Q8NC56

Background Information

Uniprot Id

Q8NC56
Target Species

Human
Target Name

LEMD2
Target Full Name

LEM domain-containing protein 2
Target Function

Involved in nuclear structure organization. Required for maintaining the integrity of the nuclear envelope.; Required for embryonic development and is involved in regulation of several signaling pathways such as MAPK and AKT. Required for myoblast differentiation involving regulation of ERK signaling.
Target Involvement

Cataract 46, juvenile-onset (CTRCT46)
Target Subcellular Location

Nucleus inner membrane; Multi-pass membrane protein. Note=Lamina-associated protein residing in the inner nuclear membrane (INM). Localized exclusively to the nuclear envelope, giving rise to a typical rim-like staining of the nuclear periphery.
Target Tissue Specificity

Ubiquitously expressed.
Target Synonyms

LEMD2; LEM domain-containing protein 2; hLEM2
Target Background

This gene encodes a LEM domain-containing transmembrane protein of the inner nuclear membrane. The protein is involved in nuclear structure organization and plays a role in cell signaling and differentiation. Mutations in this gene result in Cataract 46, juvenile-onset. Multiple transcript variants have been found for this gene.

Rabbit anti-Human LEMD2 Polyclonal Antibody

Specifications

Immunogen Information

Inquire Rabbit anti-Human LEMD2 Polyclonal Antibody Now

Related Products