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The antibody against Piezo was raised in rabbit using the Recombinant Drosophila melanogaster (Fruit fly) Piezo protein (1838-1917aa) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.
The antibody against Piezo was raised in rabbit using the Recombinant Drosophila melanogaster (Fruit fly) Piezo protein (1838-1917aa) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.
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Western Blot | Positive WB detected in: recombinant protein | All lanes: Piezo Antibody at 1:1000 | Secondary | Goat polyclonal to rabbit IgG at 1/50000 dilution | Predicted band size: 42 kDa | Observed band size: 42 kDa
| Cat.No | ADC-55387A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | Piezo |
| Target Synonyms | Piezo-type mechanosensitive ion channel component Piezo CG18103 | Form | Liquid |
| Species Reactivity | Drosophila melanogaster (Fruit fly) | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Immunogen Description | Recombinant Drosophila melanogaster (Fruit fly) Piezo protein (1838-1917aa) | Target Species | Drosophila melanogaster (Fruit fly) |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | M9MSG8 |
Uniprot Id
M9MSG8
Target Species
Drosophila melanogaster
Target Name
PIEZO
Target Function
Component of a mechanosensitive channel required for rapidly adapting mechanically activated (MA) currents. Plays a major role in nociception (response to strong or painful touch). Required for maintaining the mechanosensitivity of tarsal bristle mechanosensors. During their evalulation of potential egg-laying sites, females determine the softest substrate for their eggs first by making a coarse evaluation of substrate hardness using mechanosensitive channels nan and Piezo in the leg tarsal bristles, followed by a much finer assessment using nan, iav and Tmc mechanosensitive channels on the labellum. Acts in the nompC- and nan-expressing neurons of the female leg tarsals, to sense the mild differences in egg-laying substrate stiffness.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein.
Target Protein Families
PIEZO (TC 1.A.75) family
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