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The antibody against ABT1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-272 of human ABT1 (NP_037507.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against ABT1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-272 of human ABT1 (NP_037507.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-03629A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ABT1 |
| Target Synonyms | Esf2; hABT1; ABT1 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, Mouse heart, HepG2, Jurkat, MCF7, Mouse liver, Rat liver | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-272 of human ABT1 (NP_037507.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9ULW3 | Immunogen Sequence |
Uniprot Id
Q9ULW3
Target Species
Human
Target Name
ABT1
Target Full Name
Activator of basal transcription 1
Target Function
Could be a novel TATA-binding protein (TBP) which can function as a basal transcription activator. Can act as a regulator of basal transcription for class II genes.
Target Subcellular Location
Nucleus. Nucleus, nucleolus.
Target Protein Families
ESF2/ABP1 family
Target Synonyms
ABT1; ABT1_HUMAN; Activator of basal transcription 1; Basal transcriptional activator 1; Basal transcriptional activator; hABT1; HGNC:17369; OTTHUMP00000017935; TATA-binding protein-binding protein
Target Background
Basal transcription of genes by RNA polymerase II requires the interaction of TATA-binding protein (TBP) with the core region of class II promoters. Studies in mouse suggest that the protein encoded by this gene likely activates basal transcription from class II promoters by interaction with TBP and the class II promoter DNA.
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