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The antibody against AQR was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 400-700 of human AQR (NP_055506.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
The antibody against AQR was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 400-700 of human AQR (NP_055506.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
| Cat.No | ADA-09619A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | AQR |
| Target Synonyms | IBP160; fSAP164; AQR | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, A-549, HepG2, Jurkat, MCF7 | Application | ELISA, WB, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 400-700 of human AQR (NP_055506.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | O60306 | Immunogen Sequence |
Uniprot Id
O60306
Target Species
Human
Target Name
AQR
Target Full Name
RNA helicase aquarius
Target Function
Involved in pre-mRNA splicing as component of the spliceosome. Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre-mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing. Has ATP-dependent RNA helicase activity and can unwind double-stranded RNA molecules with a 3' overhang (in vitro)
Target Subcellular Location
Nucleus. Nucleus, nucleoplasm.
Target Protein Families
CWF11 family
Target Synonyms
AQR; AQR_HUMAN; aquarius; aquarius homolog (mouse); Aquarius intron binding spliceosomal factor; DKFZp686B23123; fSAP164; functional spliceosome-associated protein 164; IBP160; Intron-binding protein aquarius; Intron-binding protein of 160 kDa; KIAA0560
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