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Rabbit anti-Human ARL4D Polyclonal Antibody

The antibody against ARL4D was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 92-201 of human ARL4D (NP_001652.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.

ADA-06556A

The antibody against ARL4D was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 92-201 of human ARL4D (NP_001652.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.

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Specifications


Cat.No ADA-06556A ClonalityPolyclonal
Host SpeciesRabbitTarget NameARL4D
Target SynonymsARF4L; ARL4DFormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesHeLa, Mouse liverApplicationELISA, WB, IHC-P

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 92-201 of human ARL4D (NP_001652.2).Target SpeciesHuman
Immunogen SequenceRRTDGLVFVVDAAEAERLEEAKVELHRISRASDNQGVPVLVLANKQDQPGALSAAEVEKRLAVRELAAATLTHVQGCSAVDGLGLQQGLERLYEMILKRKKAARGGKKRRUniprot IDP49703
Background Information
  • Uniprot Id

    P49703

  • Target Species

    Human

  • Target Name

    ARL4D

  • Target Full Name

    ADP-ribosylation factor-like protein 4D

  • Target Function

    Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Recruits CYTH1, CYTH2, CYTH3 and CYTH4 to the plasma membrane in GDP-bound form.

  • Target Subcellular Location

    Nucleus, nucleolus. Cell membrane. Nucleus. Cytoplasm.

  • Target Protein Families

    Small GTPase superfamily, Arf family

  • Target Research Area

    Signal Transduction

  • Target Synonyms

    ADP ribosylation factor 4 like; ADP ribosylation factor like 4D; ADP ribosylation factor like 6; ADP ribosylation factor like protein 4D; ADP ribosylation factor like protein 4L; ADP-ribosylation factor-like protein 4D; ADP-ribosylation factor-like protein 4L; AR L6; ARF 4L; ARF4L; ARL 4D; ARL 6; ARL4D; ARL4D_HUMAN; ARL6

  • Target Background

    ADP-ribosylation factor 4D is a member of the ADP-ribosylation factor family of GTP-binding proteins. ARL4D is closely similar to ARL4A and ARL4C and each has a nuclear localization signal and an unusually high guanine nucleotide exchange rate. This protein may play a role in membrane-associated intracellular trafficking.

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