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The antibody against ASB3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-145 of human ASB3 (NP_057199.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.
The antibody against ASB3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-145 of human ASB3 (NP_057199.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.
| Cat.No | ADA-01745A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ASB3 |
| Target Synonyms | ASB-3; ASB3 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | 293T, A-549, Mouse testis | Application | ELISA, WB, IF/ICC, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-145 of human ASB3 (NP_057199.1). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | MDFTEAYADTCSTVGLAAREGNVKVLRKLLKKGRSVDVADNRGWMPIHEAAYHNSVECLQMLINADSSENYIKMKTFEGFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHGANVNGSHSMC | Uniprot ID | Q9Y575 |
Uniprot Id
Q9Y575
Target Species
Human
Target Name
ASB3
Target Full Name
Ankyrin repeat and SOCS box protein 3
Target Function
Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes TNFRSF1B.
Target Protein Families
Ankyrin SOCS box (ASB) family
Target Synonyms
ASB3Ankyrin repeat and SOCS box protein 3; ASB-3
Target Background
The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Alternatively spliced transcript variants have been described for this gene.
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