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Rabbit anti-Human C19orf10 Polyclonal Antibody

The antibody against C19orf10 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-173 of human C19orf10 (NP_061980.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.

ADA-01720A

The antibody against C19orf10 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-173 of human C19orf10 (NP_061980.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.

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Specifications


Cat.No ADA-01720A ClonalityPolyclonal
Host SpeciesRabbitTarget NameC19orf10
Target SynonymsIL25; IL27; SF20; IL27w; C19orf10; R33729_1; EUROIMAGE1875335FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive Samples293T, A-431, Mouse liver, Rat pancreasApplicationELISA, WB, IHC-P

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 1-173 of human C19orf10 (NP_061980.1).Target SpeciesHuman
Immunogen SequenceMAAPSGGWNGVGASLWAALLLGAVALRPAEAVSEPTTVAFDVRPGGVVHSFSHNVGPGDKYTCMFTYASQGGTNEQWQMSLGTSEDHQHFTCTIWRPQGKSYLYFTQFKAEVRGAEIEYAMAYSKAAFERESDVPLKTEEFEVTKTAVAHRPGAFKAELSKLVIVAKASRTELUniprot IDQ969H8
Background Information
  • Uniprot Id

    Q969H8

  • Target Species

    Human

  • Target Name

    MYDGF

  • Target Full Name

    Myeloid-derived growth factor

  • Target Function

    Bone marrow-derived monocyte and paracrine-acting protein that promotes cardiac myocyte survival and adaptive angiogenesis for cardiac protection and/or repair after myocardial infarction (MI). Stimulates endothelial cell proliferation through a MAPK1/3-, STAT3- and CCND1-mediated signaling pathway. Inhibits cardiac myocyte apoptosis in a PI3K/AKT-dependent signaling pathway. Involved in endothelial cell proliferation and angiogenesis.

  • Target Subcellular Location

    Secreted. Endoplasmic reticulum-Golgi intermediate compartment. Endoplasmic reticulum. Golgi apparatus.

  • Target Protein Families

    MYDGF family

  • Target Tissue Specificity

    Expressed in eosinophils (at protein level). Expressed in bone marrow cells. Expressed in synovial tissue. Found in synovial fluid of patients with arthropaties.

  • Target Synonyms

    C19orf10; Chromosome 19 open reading frame 10; CS010_HUMAN; EUROIMAGE1875335; IL 25; IL 27; IL-25; IL25; IL27; IL27w; Interleukin 25; Interleukin 27 working designation ; Interleukin-25; Interleukin25; R33729 1; R337291; SF20 ; Stromal cell derived growth factor; Stromal cell derived growth factor SF20; Stromal cell-derived growth factor SF20; Uncharacterized protein C19orf10 precursor; UPF0556 protein C19orf10

  • Target Background

    The protein encoded by this gene was previously thought to support proliferation of lymphoid cells and was considered an interleukin. However, this activity has not been reproducible and the function of this protein is currently unknown.

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