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Rabbit anti-Human C1QTNF4 Polyclonal Antibody

The antibody against C1QTNF4 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 250-329 of human C1QTNF4 (NP_114115.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-01078A

The antibody against C1QTNF4 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 250-329 of human C1QTNF4 (NP_114115.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-01078A ClonalityPolyclonal
Host SpeciesRabbitTarget NameC1QTNF4
Target SynonymsCTRP4; ZACRP4; C1QTNF4FormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesDU145, U-87MGApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 250-329 of human C1QTNF4 (NP_114115.2).Target SpeciesHuman
Immunogen SequenceNRDEVQAMIYDDGASRRREMQSQSVMLALRRGDAVWLLSHDHDGYGAYSNHGKYITFSGFLVYPDLAPAAPPGLGASELLUniprot IDQ9BXJ3
Background Information
  • Uniprot Id

    Q9BXJ3

  • Target Species

    Human

  • Target Name

    C1QTNF4

  • Target Full Name

    Complement C1q tumor necrosis factor-related protein 4

  • Target Function

    May be involved in the regulation of the inflammatory network. Its role as pro- or anti-inflammatory seems to be context dependent. Seems to have some role in regulating food intake and energy balance when administered in the brain. This effect is sustained over a two-day period, and it is accompanied by decreased expression of orexigenic neuropeptides in the hypothalamus 3 hours post-injection.

  • Target Subcellular Location

    Secreted.

  • Target Tissue Specificity

    Widely expressed at low levels. Highest levels in adipocyte tissue and brain.

  • Target Synonyms

    C1QTNF4; CTRP4Complement C1q tumor necrosis factor-related protein 4; C1q/TNF-related protein 4

  • Target Background

    Predicted to enable cytokine activity. Involved in positive regulation of cytokine production and positive regulation of signal transduction. Located in extracellular space.

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