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Rabbit anti-Human C2CD5 Polyclonal Antibody

The antibody against C2CD5 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 732-1051 of human C2CD5 (NP_001273103.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-05694A

The antibody against C2CD5 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 732-1051 of human C2CD5 (NP_001273103.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-05694A ClonalityPolyclonal
Host SpeciesRabbitTarget NameC2CD5
Target SynonymsCDP138; KIAA0528; C2CD5FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesHeLa, A-549, HepG2, Jurkat, Mouse brain, Rat liver, U-251MGApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 732-1051 of human C2CD5 (NP_001273103.1).Target SpeciesHuman
Uniprot IDQ86YS7Immunogen Sequence
Background Information
  • Uniprot Id

    Q86YS7

  • Target Species

    Human

  • Target Name

    C2CD5

  • Target Full Name

    C2 domain-containing protein 5

  • Target Function

    Required for insulin-stimulated glucose transport and glucose transporter SLC2A4/GLUT4 translocation from intracellular glucose storage vesicle (GSV) to the plasma membrane (PM) in adipocytes. Binds phospholipid membranes in a calcium-dependent manner and is necessary for the optimal membrane fusion between SLC2A4/GLUT4 GSV and the PM.

  • Target Subcellular Location

    Cytoplasmic vesicle membrane. Cytoplasm, cell cortex. Cell membrane. Cell projection, ruffle. Note=Dynamically associated with GLUT4-containing glucose storage vesicles (GSV) and plasma membrane in response to insulin stimulation.

  • Target Synonyms

    C2CD5; CDP138; KIAA0528C2 domain-containing protein 5; C2 domain-containing phosphoprotein of 138 kDa

  • Target Background

    Enables calcium ion binding activity and calcium-dependent phospholipid binding activity. Involved in cellular response to insulin stimulus; intracellular protein transmembrane transport; and positive regulation of transport. Located in several cellular components, including centriolar satellite; cytoplasmic vesicle membrane; and ruffle membrane.

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