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The antibody against CAPRIN1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human CAPRIN1 (NP_005889.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
The antibody against CAPRIN1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human CAPRIN1 (NP_005889.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
| Cat.No | ADA-10964A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CAPRIN1 |
| Target Synonyms | M11S1; GPIAP1; RNG105; GPIP137; GRIP137; p137GPI; CAPRIN1 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.05% proclin300, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, Mouse brain | Application | ELISA, WB, IF/ICC |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human CAPRIN1 (NP_005889.3). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q14444 | Immunogen Sequence |
Uniprot Id
Q14444
Target Species
Human
Target Name
CAPRIN1
Target Full Name
Caprin-1
Target Function
May regulate the transport and translation of mRNAs of proteins involved in synaptic plasticity in neurons and cell proliferation and migration in multiple cell types. Binds directly and selectively to MYC and CCND2 RNAs. In neuronal cells, directly binds to several mRNAs associated with RNA granules, including BDNF, CAMK2A, CREB1, MAP2, NTRK2 mRNAs, as well as to GRIN1 and KPNB1 mRNAs, but not to rRNAs.
Target Subcellular Location
Cytoplasm, cytosol. Cell projection, dendrite. Cell projection, lamellipodium.
Target Protein Families
Caprin family
Target Tissue Specificity
Ubiquitous.
Target Research Area
Others
Target Synonyms
activation/proliferation-associated protein 1; CAPR1_HUMAN; Caprin-1; CAPRIN1; Cell cycle-associated protein 1; Cytoplasmic activation- and proliferation-associated protein 1; cytoplasmic activation/proliferation-associated protein-1; GPI-anchored membrane protein 1; GPI-anchored protein p137; GPI-p137; GPIAP1; GPIP137; M11S1; Membrane component chromosome 11 surface marker 1; p137GPI; RNA granule protein 105; RNG105
Target Background
Enables RNA binding activity. Predicted to be involved in negative regulation of translation and positive regulation of dendritic spine morphogenesis. Located in cell leading edge and cytosol.
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