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The antibody against CFAP53 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human CFAP53 (NP_659457.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
The antibody against CFAP53 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human CFAP53 (NP_659457.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
| Cat.No | ADA-08718A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CFAP53 |
| Target Synonyms | HTX6; CCDC11; CFAP53 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse testis, Rat testis | Application | ELISA, WB, IF/ICC |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human CFAP53 (NP_659457.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q96M91 | Immunogen Sequence |
Uniprot Id
Q96M91
Target Species
Human
Target Name
CFAP53
Target Full Name
Cilia- and flagella-associated protein 53
Target Function
May play a role in the beating of primary cilia and thereby be involved in the establishment of organ laterality during embryogenesis.
Target Involvement
Heterotaxy, visceral, 6, autosomal (HTX6)
Target Subcellular Location
Cell projection, cilium.
Target Protein Families
CFAP53 family
Target Tissue Specificity
Expressed in skin fibroblasts (at protein level).
Target Synonyms
4933415I03Rik; CCD11_HUMAN; CCDC11; Cilia and flagella associated protein 53; Coiled coil domain containing 11; Coiled coil domain containing protein 11; Coiled-coil domain-containing protein 11; FLJ32743; HTX6; MGC117752; RGD1306734
Target Background
This gene belongs to the CFAP53 family. It was found to be differentially expressed by the ciliated cells of frog epidermis and in skin fibroblasts from human. Mutations in this gene are associated with visceral heterotaxy-6, which implicates this gene in determination of left-right asymmetric patterning.
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