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The antibody against CHKA was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-170 of human CHKA (NP_001268.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against CHKA was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-170 of human CHKA (NP_001268.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-10149A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CHKA |
| Target Synonyms | CK; EK; CHK; CKI; NEDMIMS; CHKA | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HepG2, Jurkat, Mouse brain, Rat testis | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-170 of human CHKA (NP_001268.2). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | MKTKFCTGGEAEPSPLGLLLSCGSGSAAPAPGVGQQRDAASDLESKQLGGQQPPLALPPPPPLPLPLPLPQPPPPQPPADEQPEPRTRRRAYLWCKEFLPGAWRGLREDEFHISVIRGGLSNMLFQCSLPDTTATLGDEPRKVLLRLYGAILQMRSCNKEGSEQAQKENE | Uniprot ID | P35790 |
Uniprot Id
P35790
Target Species
Human
Target Name
CHKA
Target Full Name
Choline kinase alpha
Target Function
Has a key role in phospholipid biosynthesis and may contribute to tumor cell growth. Catalyzes the first step in phosphatidylcholine biosynthesis. Contributes to phosphatidylethanolamine biosynthesis. Phosphorylates choline and ethanolamine. Has higher activity with choline.
Target Subcellular Location
Cytoplasm.
Target Protein Families
Choline/ethanolamine kinase family
Target Synonyms
CHKA; CHK; CKI; Choline kinase alpha; CK; EC 2.7.1.32; CHETK-alpha; Ethanolamine kinase; EK; EC 2.7.1.82
Target Background
The major pathway for the biosynthesis of phosphatidylcholine occurs via the CDP-choline pathway. The protein encoded by this gene is the initial enzyme in the sequence and may play a regulatory role. The encoded protein also catalyzes the phosphorylation of ethanolamine. Two transcript variants encoding different isoforms have been found for this gene.
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