Rabbit anti-Human CIRBP Polyclonal Antibody

The antibody against CIRBP was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-172 of human CIRBP (NP_001271.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.

ADA-15896A

Number

Cat.No	ADA-15896A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	CIRBP
Target Synonyms	CIRP; BP	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	293T, HepG2, Jurkat, Mouse brain, Mouse testis, U-251MG	Application	ELISA, WB, IF/ICC, IHC-P

Cat.No

ADA-15896A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

CIRBP

Target Synonyms

CIRP; BP

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

293T, HepG2, Jurkat, Mouse brain, Mouse testis, U-251MG

Application

ELISA, WB, IF/ICC, IHC-P

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 1-172 of human CIRBP (NP_001271.1).	Target Species	Human
Immunogen Sequence	MASDEGKLFVGGLSFDTNEQSLEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMAMNGKSVDGRQIRVDQAGKSSDNRSRGYRGGSAGGRGFFRGGRGRGRGFSRGGGDRGYGGNRFESRSGGYGGSRDYYSSRSQSGGYSDRSSGGSYRDSYDSYATHNE	Uniprot ID	Q14011

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 1-172 of human CIRBP (NP_001271.1).

Target Species

Human

Immunogen Sequence

MASDEGKLFVGGLSFDTNEQSLEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMAMNGKSVDGRQIRVDQAGKSSDNRSRGYRGGSAGGRGFFRGGRGRGRGFSRGGGDRGYGGNRFESRSGGYGGSRDYYSSRSQSGGYSDRSSGGSYRDSYDSYATHNE

Uniprot ID

Q14011

Background Information

Uniprot Id

Q14011
Target Species

Human
Target Name

CIRBP
Target Full Name

Cold-inducible RNA-binding protein
Target Function

Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor. Promotes assembly of stress granules (SGs), when overexpressed.
Target Subcellular Location

Nucleus, nucleoplasm. Cytoplasm.
Target Tissue Specificity

Ubiquitous.
Target Research Area

Cell Biology, Epigenetics and Nuclear Signaling
Target Synonyms

A18 hnRNP; A18HNRNP; cirbp; CIRBP_HUMAN; CIRP; Cold inducible RNA binding protein; Cold-inducible RNA-binding protein; Glycine rich RNA binding protein; Glycine-rich RNA-binding protein CIRP; testicular tissue protein Li 39
Target Background

Enables mRNA 3'-UTR binding activity and small ribosomal subunit rRNA binding activity. Involved in mRNA stabilization; positive regulation of translation; and response to UV. Located in cytoplasm and nucleoplasm.

Rabbit anti-Human CIRBP Polyclonal Antibody

Specifications

Immunogen Information

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