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Rabbit anti-Human CLCA4 Polyclonal Antibody

The antibody against CLCA4 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 22-150 of human CLCA4 (NP_036260.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-06990A

The antibody against CLCA4 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 22-150 of human CLCA4 (NP_036260.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-06990A ClonalityPolyclonal
Host SpeciesRabbitTarget NameCLCA4
Target SynonymsCaCC; CaCC2; CLCA4FormLiquid
Species ReactivityHuman, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesHeLa, 293T, Rat uterusApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 22-150 of human CLCA4 (NP_036260.2).Target SpeciesHuman
Immunogen SequenceSFIKLNNNGFEDIVIVIDPSVPEDEKIIEQIEDMVTTASTYLFEATEKRFFFKNVSILIPENWKENPQYKRPKHENHKHADVIVAPPTLPGRDEPYTKQFTECGEKGEYIHFTPDLLLGKKQNEYGPPGUniprot IDQ14CN2
Background Information
  • Uniprot Id

    Q14CN2

  • Target Species

    Human

  • Target Name

    CLCA4

  • Target Full Name

    Calcium-activated chloride channel regulator 4

  • Target Function

    May be involved in mediating calcium-activated chloride conductance.

  • Target Subcellular Location

    Cell membrane; Single-pass membrane protein. Apical cell membrane. Secreted.

  • Target Protein Families

    CLCR family

  • Target Tissue Specificity

    Primarily expressed in the digestive tract, mainly in colon. Detected in smaller amounts in brain, urogenital organs, testis, and salivary and mammary glands. Highly expressed in the epithelial layer and submucosal gland of the inferior turbinate mucosa.

  • Target Synonyms

    30 kDa form; CaCC-2; Calcium-activated chloride channel family member 4; Calcium-activated chloride channel protein 2; Calcium-activated chloride channel regulator 4; Clca4; CLCA4_HUMAN; hCaCC-2; hCLCA4

  • Target Background

    The protein encoded by this gene belongs to the calcium sensitive chloride conductance protein family. To date, all members of this gene family map to the same site on chromosome 1p31-p22 and share high degrees of homology in size, sequence and predicted structure, but differ significantly in their tissue distributions. Alternative splicing results in multiple transcript variants, only one of which is thought to be protein coding.

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