Rabbit anti-Human CPSF1 Polyclonal Antibody

The antibody against CPSF1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 700-950 of human CPSF1 (NP_037423.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-06050A

Number

Cat.No	ADA-06050A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	CPSF1
Target Synonyms	MYP27; CPSF160; P/cl.18; HSU37012; CPSF1	Form	Liquid
Species Reactivity	Human, Mouse	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	NIH/3T3, 293T, Mouse liver	Application	ELISA, WB

Cat.No

ADA-06050A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

CPSF1

Target Synonyms

MYP27; CPSF160; P/cl.18; HSU37012; CPSF1

Form

Liquid

Species Reactivity

Human, Mouse

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

NIH/3T3, 293T, Mouse liver

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 700-950 of human CPSF1 (NP_037423.2).	Target Species	Human
Uniprot ID	Q10570	Immunogen Sequence

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 700-950 of human CPSF1 (NP_037423.2).

Target Species

Human

Uniprot ID

Q10570

Immunogen Sequence

Background Information

Uniprot Id

Q10570
Target Species

Human
Target Name

CPSF1
Target Full Name

Cleavage and polyadenylation specificity factor subunit 1
Target Function

Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction. May play a role in eye morphogenesis and the development of retinal ganglion cell projections to the midbrain.
Target Subcellular Location

Nucleus, nucleoplasm.
Target Protein Families

CPSF1 family
Target Tissue Specificity

Widely expressed, with high expression in the retina.
Target Synonyms

CPSF1; CPSF160Cleavage and polyadenylation specificity factor subunit 1; Cleavage and polyadenylation specificity factor 160 kDa subunit; CPSF 160 kDa subunit
Target Background

Cleavage and polyadenylation specificity factor (CPSF) is a multisubunit complex that plays a central role in 3-prime processing of pre-mRNAs. CPSF recognizes the AAUAAA signal in the pre-mRNA and interacts with other proteins to facilitate both RNA cleavage and poly(A) synthesis. CPSF1 is the largest subunit of the CPSF complex (Murthy and Manley, 1995 [PubMed 7590244]).

Rabbit anti-Human CPSF1 Polyclonal Antibody

Specifications

Immunogen Information

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