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The antibody against CRTAP was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 20-240 of human CRTAP (NP_006362.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
The antibody against CRTAP was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 20-240 of human CRTAP (NP_006362.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
| Cat.No | ADA-00451A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CRTAP |
| Target Synonyms | OI7; CASP; P3H5; LEPREL3; CRTAP | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | SW480 | Application | ELISA, WB, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 20-240 of human CRTAP (NP_006362.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | O75718 | Immunogen Sequence |
Uniprot Id
O75718
Target Species
Human
Target Name
CRTAP
Target Full Name
Cartilage-associated protein
Target Function
Necessary for efficient 3-hydroxylation of fibrillar collagen prolyl residues.
Target Involvement
Osteogenesis imperfecta 7 (OI7)
Target Subcellular Location
Secreted, extracellular space, extracellular matrix.
Target Protein Families
Leprecan family
Target Tissue Specificity
Found in articular chondrocytes. Expressed in a variety of tissues.
Target Synonyms
CRTAP; CASPCartilage-associated protein
Target Background
The protein encoded by this gene is similar to the chicken and mouse CRTAP genes. The encoded protein is a scaffolding protein that may influence the activity of at least one member of the cytohesin/ARNO family in response to specific cellular stimuli. Defects in this gene are associated with osteogenesis imperfecta, a connective tissue disorder characterized by bone fragility and low bone mass.
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