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Rabbit anti-Human CSN2 Polyclonal Antibody

The antibody against CSN2 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1-100 of human CSN2 (NP_001882.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-12320A

The antibody against CSN2 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1-100 of human CSN2 (NP_001882.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-12320A ClonalityPolyclonal
Host SpeciesRabbitTarget NameCSN2
Target SynonymsCASB; PDC213; CSN2FormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesMCF7ApplicationELISA, WB

Immunogen Information


Immunogen DescriptionA synthetic peptide corresponding to a sequence within amino acids 1-100 of human CSN2 (NP_001882.1).Target SpeciesHuman
Immunogen SequenceMKVLILACLVALALARETIESLSSSEESITEYKQKVEKVKHEDQQQGEDEHQDKIYPSFQPQPLIYPFVEPIPYGFLPQNILPLAQPAVVLPVPQPEIMEUniprot IDP05814
Background Information
  • Uniprot Id

    P05814

  • Target Species

    Human

  • Target Name

    CSN2

  • Target Full Name

    Beta-casein

  • Target Function

    Important role in determination of the surface properties of the casein micelles.

  • Target Subcellular Location

    Secreted.

  • Target Protein Families

    Beta-casein family

  • Target Tissue Specificity

    Mammary gland specific. Secreted in milk.

  • Target Synonyms

    Beta-casein; CASB; CASB_HUMAN; Casein beta; CSN 2; Csn2

  • Target Background

    This gene is a member of the beta casein family. There are two types of casein protein, beta (encoded by this gene) and kappa, both of which are secreted in human milk. Beta casein is the principal protein in human milk and the primary source of essential amino acids for a suckling infant. Beta and kappa casein proteins acting together form spherical micelles which bind within them important dietary minerals, such as calcium and phosphorous. In addition, the C-terminal 14 aa of the protein has antimicrobial activity, especially in preterm milk, displaying antibacterial activity against S. aureus and Y. enterocolitica. Alternative splicing results in multiple transcript variants.

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