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Rabbit anti-Human EMB Polyclonal Antibody

The antibody against EMB was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 33-260 of human EMB (NP_940851.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-01505A

The antibody against EMB was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 33-260 of human EMB (NP_940851.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-01505A ClonalityPolyclonal
Host SpeciesRabbitTarget NameEMB
Target SynonymsGP70; EMBFormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesJurkat, MCF7, THP-1ApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 33-260 of human EMB (NP_940851.1).Target SpeciesHuman
Uniprot IDQ6PCB8Immunogen Sequence
Background Information
  • Uniprot Id

    Q6PCB8

  • Target Species

    Human

  • Target Name

    EMB

  • Target Full Name

    Embigin

  • Target Function

    Plays a role in the outgrowth of motoneurons and in the formation of neuromuscular junctions. Following muscle denervation, promotes nerve terminal sprouting and the formation of additional acetylcholine receptor clusters at synaptic sites without affecting terminal Schwann cell number or morphology. Delays the retraction of terminal sprouts following re-innervation of denervated endplates. May play a role in targeting the monocarboxylate transporters SLC16A1 and SLC16A7 to the cell membrane.

  • Target Subcellular Location

    Cell membrane; Single-pass type I membrane protein. Cell junction, synapse.

  • Target Synonyms

    Emb; EMB_HUMAN; Embigin; Embigin homolog (mouse); embigin homolog; MGC71745; OTTHUMP00000161812; OTTHUMP00000221477; OTTHUMP00000221478; OTTHUMP00000221479

  • Target Background

    This gene encodes a transmembrane glycoprotein that is a member of the immunoglobulin superfamily. The encoded protein may be involved in cell growth and development by mediating interactions between the cell and extracellular matrix. A pseudogene of this gene is found on chromosome 1.

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