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The antibody against EMB was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 33-260 of human EMB (NP_940851.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against EMB was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 33-260 of human EMB (NP_940851.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-01505A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | EMB |
| Target Synonyms | GP70; EMB | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Jurkat, MCF7, THP-1 | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 33-260 of human EMB (NP_940851.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q6PCB8 | Immunogen Sequence |
Uniprot Id
Q6PCB8
Target Species
Human
Target Name
EMB
Target Full Name
Embigin
Target Function
Plays a role in the outgrowth of motoneurons and in the formation of neuromuscular junctions. Following muscle denervation, promotes nerve terminal sprouting and the formation of additional acetylcholine receptor clusters at synaptic sites without affecting terminal Schwann cell number or morphology. Delays the retraction of terminal sprouts following re-innervation of denervated endplates. May play a role in targeting the monocarboxylate transporters SLC16A1 and SLC16A7 to the cell membrane.
Target Subcellular Location
Cell membrane; Single-pass type I membrane protein. Cell junction, synapse.
Target Synonyms
Emb; EMB_HUMAN; Embigin; Embigin homolog (mouse); embigin homolog; MGC71745; OTTHUMP00000161812; OTTHUMP00000221477; OTTHUMP00000221478; OTTHUMP00000221479
Target Background
This gene encodes a transmembrane glycoprotein that is a member of the immunoglobulin superfamily. The encoded protein may be involved in cell growth and development by mediating interactions between the cell and extracellular matrix. A pseudogene of this gene is found on chromosome 1.
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