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The antibody against GNL2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human GNL2 (NP_037417.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against GNL2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human GNL2 (NP_037417.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-09592A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | GNL2 |
| Target Synonyms | NGP1; Nog2; Nug2; Ngp-1; HUMAUANTIG; GNL2 | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | NIH/3T3 | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human GNL2 (NP_037417.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q13823 | Immunogen Sequence |
Uniprot Id
Q13823
Target Species
Human
Target Name
GNL2
Target Full Name
Nucleolar GTP-binding protein 2
Target Function
GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. May promote cell proliferation possibly by increasing p53/TP53 protein levels, and consequently those of its downstream product CDKN1A/p21, and decreasing RPL23A protein levels.
Target Subcellular Location
Nucleus, nucleolus.
Target Protein Families
TRAFAC class YlqF/YawG GTPase family, NOG2 subfamily
Target Tissue Specificity
Widely expressed, with the highest expression level in testis.
Target Research Area
Epigenetics and Nuclear Signaling
Target Synonyms
Autoantigen NGP-1; Autoantigen NGP1; DJ423B22.6 (novel nucleolar guanosine 5'-triphosphate binding protein; FLJ40906; GNL2; Guanine nucleotide binding protein-like 2 (nucleolar); HUMAUANTIG; NGP1; NOG2_HUMAN; novel nucleolar guanosine 5'-triphosphate binding protein autoantigen; nucleolar G-protein gene 1; Nucleolar GTP binding protein 2; Nucleolar GTP-binding protein 2; Nucleolar GTPase
Target Background
Enables RNA binding activity. Predicted to be involved in ribosome biogenesis. Located in nucleolus.
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