Rabbit anti-Human HASPIN Polyclonal Antibody

The antibody against HASPIN was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 290-470 of human HASPIN (NP_114171.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-07403A

Number

Cat.No	ADA-07403A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	HASPIN
Target Synonyms	GSG2; HASPIN	Form	Liquid
Species Reactivity	Human, Mouse	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	HeLa, K-562	Application	ELISA, WB

Cat.No

ADA-07403A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

HASPIN

Target Synonyms

GSG2; HASPIN

Form

Liquid

Species Reactivity

Human, Mouse

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

HeLa, K-562

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 290-470 of human HASPIN (NP_114171.2).	Target Species	Human
Immunogen Sequence	GKRRATGQDSCQERGLQEAVRREHQEASVPKGRIVPRGIDRLERTRSSRKSKHQEATETSLLHSHRFKKGQKLGKDSFPTQDLTPLQNVCFWTKTRASFSFHKKKIVTDVSEVCSIYTTATSLSGSLLSECSNRPVMNRTSGAPSSWHSSSMYLLSPLNTLSISNKKASDAEKVYGECSQK	Uniprot ID	Q8TF76

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 290-470 of human HASPIN (NP_114171.2).

Target Species

Human

Immunogen Sequence

GKRRATGQDSCQERGLQEAVRREHQEASVPKGRIVPRGIDRLERTRSSRKSKHQEATETSLLHSHRFKKGQKLGKDSFPTQDLTPLQNVCFWTKTRASFSFHKKKIVTDVSEVCSIYTTATSLSGSLLSECSNRPVMNRTSGAPSSWHSSSMYLLSPLNTLSISNKKASDAEKVYGECSQK

Uniprot ID

Q8TF76

Background Information

Uniprot Id

Q8TF76
Target Species

Human
Target Name

HASPIN
Target Full Name

Serine/threonine-protein kinase haspin
Target Function

Serine/threonine-protein kinase that phosphorylates histone H3 at 'Thr-3' (H3T3ph) during mitosis. May act through H3T3ph to both position and modulate activation of AURKB and other components of the chromosomal passenger complex (CPC) at centromeres to ensure proper chromatid cohesion, metaphase alignment and normal progression through the cell cycle.
Target Subcellular Location

Nucleus. Chromosome. Cytoplasm, cytoskeleton, spindle. Note=Nuclear during interphase and associates with the chromosomes and spindle apparatus during mitosis.
Target Protein Families

Protein kinase superfamily, Ser/Thr protein kinase family, Haspin subfamily
Target Tissue Specificity

Strongly expressed in testis. Also present in thymus and bone marrow and low levels observed in prostate, intestine, lung, spleen and lymph node. Expressed in fetal skin, liver, kidney and small intestine and also in proliferating but not non-proliferatin
Target Synonyms

germ cell associated 2; Germ cell-specific gene 2 protein; GSG2; H-haspin; Haploid germ cell-specific nuclear protein kinase; HASP_HUMAN; Serine/threonine-protein kinase haspin

Rabbit anti-Human HASPIN Polyclonal Antibody

Specifications

Immunogen Information

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