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The antibody against HAUS8 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 166-410 of human HAUS8 (NP_219485.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
The antibody against HAUS8 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 166-410 of human HAUS8 (NP_219485.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
| Cat.No | ADA-08679A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | HAUS8 |
| Target Synonyms | DGT4; HICE1; NY-SAR-48; HAUS8 | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Jurkat, Mouse testis, NCI-H460 | Application | ELISA, WB, IF/ICC |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 166-410 of human HAUS8 (NP_219485.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9BT25 | Immunogen Sequence |
Uniprot Id
Q9BT25
Target Species
Human
Target Name
HAUS8
Target Full Name
HAUS augmin-like complex subunit 8
Target Function
Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex.
Target Subcellular Location
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole.
Target Protein Families
HAUS8 family
Target Synonyms
DGT4; HAUS augmin like complex subunit 8; HAUS augmin-like complex subunit 8; HAUS8; HAUS8_HUMAN; Hec1 interacting and centrosome associated 1; HEC1/NDC80 interacting centrosome associated protein 1; HEC1/NDC80-interacting centrosome-associated protein 1; HICE 1; HICE1; MGC20533; NY SAR 48; NY-SAR-48; Sarcoma antigen NY SAR 48; Sarcoma antigen NY-SAR-48
Target Background
HAUS8 is 1 of 8 subunits of the 390-kD human augmin complex, or HAUS complex. The augmin complex was first identified in Drosophila, and its name comes from the Latin verb 'augmentare, ' meaning 'to increase.' The augmin complex is a microtubule-binding complex involved in microtubule generation within the mitotic spindle and is vital to mitotic spindle assembly (Goshima et al., 2008 [PubMed 18443220]; Uehara et al., 2009 [PubMed 19369198]).
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